Introduction
Despite decades of health financing reforms, patients across the world continue to face high treatment costs, even when insured. In 2025, health insurance coverage has expanded globally, yet out-of-pocket (OOP) expenditure remains a major driver of financial hardship, particularly for people living with chronic diseases, cancer, and rare conditions.
According to the World Health Organization (WHO), nearly 2 billion people globally still experience financial hardship due to healthcare spending, with medicines accounting for the largest share of out-of-pocket payments in many low- and middle-income countries (LMICs). Even in high-income countries, rising insurance premiums, deductibles, and co-payments are shifting costs from insurers to patients.
This article provides an evidence-based analysis of health insurance and treatment costs in 2025, examining why care remains expensive, how insurance design contributes to patient burden, and what policy solutions can realistically improve affordability.
Further Reading:
Understanding the True Cost of Healthcare
Healthcare costs are driven by multiple interlinked components, including:
- Medicine prices and markups
- Diagnostic and laboratory services
- Hospitalization and specialist fees
- Administrative and insurance overhead
- Long-term care for chronic diseases
While insurance is designed to pool risk and reduce individual financial exposure, insurance alone does not control prices. In many systems, insurance actually enables higher prices by guaranteeing payment.
Globally, medicines remain the single largest cost driver for patients, particularly where reimbursement lists are limited or cost-sharing is high.
Global Trends in Health Insurance Coverage
Expansion Without Full Protection
Over the past decade, many countries have expanded health insurance coverage through:
- Universal Health Coverage (UHC) schemes
- Social health insurance
- Community-based health insurance
- Private insurance markets
However, coverage does not equal financial protection.
WHO data consistently show that countries may report high insurance enrollment rates while still experiencing:
- High catastrophic health expenditure
- Delayed care due to cost
- Treatment non-adherence
This gap is largely explained by benefit package limitations and cost-sharing mechanisms.
Out-of-Pocket Spending: The Persistent Problem
What Counts as Out-of-Pocket Costs?
Out-of-pocket spending includes:
- Co-payments for consultations
- Deductibles
- Non-covered medicines
- Diagnostic tests outside benefit packages
- Informal payments in some settings
WHO defines catastrophic health expenditure as spending exceeding 10–25% of household income, a threshold still crossed by millions of households each year.
Medicines as the Main Cost Driver
In many LMICs, medicines account for 30–60% of total health expenditure, compared to 10–20% in most high-income countries. This imbalance explains why insurance schemes that fail to comprehensively cover medicines provide limited financial protection.
For a deeper policy perspective, see our analysis of effective drug pricing policies and regulatory frameworks, which explores how governments can reduce medicine costs through evidence-based interventions.
Insurance Design and Its Impact on Treatment Costs
Deductibles and Co-Payments
In private and mixed insurance systems, high deductibles and co-payments are increasingly common. These mechanisms are intended to reduce unnecessary utilization but often:
- Discourage timely care
- Increase long-term costs
- Disproportionately affect low-income patients
Narrow Benefit Packages
Many insurance schemes exclude:
- New medicines
- Specialized diagnostics
- Long-term rehabilitation
- Mental health services
As a result, patients remain insured on paper but under-protected in practice.
Treatment Costs for Chronic Diseases
The Long-Term Financial Burden
Chronic diseases such as diabetes, hypertension, asthma, and cardiovascular disease require lifelong treatment, making affordability a sustained concern.
Evidence from multiple health systems shows that:
- Patients with chronic illness spend significantly more out-of-pocket
- Medication non-adherence increases when co-payments rise
- Poor adherence leads to higher hospitalization rates
This creates a cost spiral where short-term savings in insurance budgets result in long-term system inefficiency.
Cancer Treatment Costs and Insurance Gaps
Cancer remains one of the most financially devastating conditions worldwide. Even in insured populations:
- New oncology medicines are frequently excluded or partially covered
- Diagnostic delays increase total treatment costs
- Patients face indirect costs such as travel and income loss
Our detailed review on equitable access to cancer medicines highlights how pricing policies, reimbursement delays, and supply chain inefficiencies restrict access even in countries with formal insurance coverage.
Why Insurance Alone Cannot Control Prices
The Price-Setting Problem
Insurance systems typically pay prices rather than set them. Without strong regulation, insurers may reimburse:
- High launch prices for new medicines
- Inefficient service delivery models
- Fragmented care pathways
Countries that successfully control costs rely on:
- Price regulation
- Health technology assessment (HTA)
- International price benchmarking
For example, comparing how countries set reimbursement prices through international benchmarking mechanisms has been shown to reduce excessive price variation and improve affordability.
Private Insurance and Cost Inflation
Private insurance markets often contribute to rising costs by:
- Encouraging supplier-induced demand
- Negotiating prices without transparency
- Segmenting risk pools
In several OECD countries, private insurance complements public systems but still increases total health expenditure due to administrative overhead and profit margins.
Health Insurance in Low- and Middle-Income Countries
Coverage Expansion vs. Service Availability
In many LMICs, insurance coverage has expanded faster than health system capacity. This results in:
- Stock-outs of essential medicines
- Limited provider networks
- Continued reliance on private pharmacies
When essential medicines are unavailable in public facilities, insured patients are forced to pay out-of-pocket, reinforcing inequities.
This challenge is explored in detail in our article on why essential medicines remain unaffordable, which examines structural and financing barriers beyond insurance coverage.
Policy Tools That Reduce Treatment Costs
1. Strategic Purchasing
Purchasing services and medicines based on value, not volume, allows insurers to:
- Negotiate better prices
- Prioritize cost-effective interventions
- Reduce waste
2. Essential Medicines Coverage
Expanding reimbursement of WHO-listed essential medicines has consistently reduced catastrophic spending.
3. Price Regulation and Transparency
Countries with transparent pricing frameworks experience:
- Lower medicine prices
- Reduced price variation
- Improved public trust
For a systems-level view, our guide on building effective pharmaceutical pricing systems outlines key regulatory pillars for sustainable cost control.
Digital Health and Cost Efficiency
Digital health tools increasingly support insurance systems by:
- Reducing administrative costs
- Improving claims processing
- Supporting remote monitoring
However, digitalization alone does not reduce prices unless paired with policy reform and benefit redesign.
The Role of Pharmacists in Cost Containment
Pharmacists play a critical role in:
- Generic substitution
- Medication therapy management
- Preventing irrational medicine use
Evidence shows that pharmacist-led interventions reduce both medicine costs and hospitalization rates, particularly for chronic diseases.
Future Outlook: What Must Change by 2030
If current trends continue, health insurance expansion without cost control will:
- Increase public expenditure
- Worsen household financial strain
- Undermine trust in health systems
Sustainable solutions require:
- Strong price regulation
- Comprehensive benefit packages
- Evidence-based reimbursement decisions
- Cross-sector collaboration
Conclusion
In 2025, health insurance remains a necessary but insufficient tool for protecting patients from high treatment costs. Without addressing medicine prices, benefit design, and systemic inefficiencies, insurance coverage alone cannot deliver financial protection.
Reducing treatment costs requires coordinated policy action, combining insurance reform with pharmaceutical pricing regulation, strategic purchasing, and health system strengthening. Only then can insurance fulfill its promise of equitable, affordable care.
Frequently Asked Questions (FAQs)
Why do insured patients still pay high treatment costs?
Because many insurance schemes include co-payments, deductibles, and limited benefit packages that exclude essential medicines and diagnostics.
Are medicines the biggest contributor to out-of-pocket spending?
Yes. In many countries, medicines account for the largest share of household health expenditure, especially where reimbursement is limited.
Does expanding insurance coverage reduce costs?
Coverage improves access but does not automatically reduce prices. Cost control requires price regulation and value-based purchasing.
How can governments reduce treatment costs?
Through price regulation, essential medicines coverage, international benchmarking, and strategic purchasing mechanisms.
Will digital health reduce healthcare costs?
Digital tools improve efficiency, but meaningful cost reduction depends on broader policy and financing reforms.

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