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The Insight Corner Hub: Drug-Related Problems Among Patients with Heart Diseases and Their Comorbid Conditions Drug-Related Problems Among Patients with Heart Diseases and Their Comorbid Conditions

Abstract

Patients with heart diseases often present with comorbid conditions that require complex medication regimens. This article explores the challenges and potential drug-related problems faced by these patients, including drug interactions, adverse effects, non-adherence, and polypharmacy. It emphasizes the importance of comprehensive medication management, interdisciplinary healthcare teams, and patient education to optimize treatment outcomes.

Introduction

Heart diseases are a leading cause of morbidity and mortality worldwide, often occurring alongside other chronic conditions, such as diabetes, hypertension, and kidney disease. These comorbidities necessitate multiple medications, which can pose significant challenges and potential drug-related problems for patients. This article examines the complexities of medication management among individuals with heart diseases and their comorbid conditions, highlighting the importance of a holistic approach to care.

Challenges Faced by Patients

1. Drug Interactions: Patients with heart diseases often take several medications, increasing the risk of drug interactions. These interactions can lead to reduced effectiveness, increased side effects, or adverse events (Meredith, 2016).

2. Adverse Effects: Medications prescribed for heart diseases, such as antiplatelet agents, beta-blockers, and ACE inhibitors, can cause adverse effects like dizziness, fatigue, and gastrointestinal disturbances (Yusuf et al., 2008).

3. Non-Adherence: Patients may struggle with medication adherence due to the complexity of their regimens, side effects, or cost-related issues. Non-adherence can result in treatment failure or exacerbation of comorbid conditions (Sokol et al., 2005).

4. Polypharmacy: Managing multiple medications can be overwhelming, increasing the likelihood of medication errors and inappropriate drug use (Gnjidic et al., 2012).

Addressing Drug-Related Problems

1. Comprehensive Medication Management: Healthcare providers should conduct thorough medication reviews, assess drug interactions, and adjust treatment plans accordingly (Meredith, 2016). This approach promotes safer and more effective medication use.

2. Interdisciplinary Healthcare Teams: Collaboration among healthcare professionals, including cardiologists, pharmacists, nurses, and primary care providers, is vital. A team-based approach ensures comprehensive patient care, reducing the risk of drug-related problems (Page et al., 2019).

3. Patient Education: Empowering patients with knowledge about their medications, potential side effects, and the importance of adherence is crucial. Education can enhance self-management and improve treatment outcomes (Vrijens et al., 2012).

4. Simplification of Regimens: Whenever possible, healthcare providers should simplify medication regimens to reduce the burden on patients. This may involve using combination pills or once-daily dosing to enhance adherence (Gislason et al., 2011).

Conclusion

Patients with heart diseases and comorbid conditions face numerous challenges related to medication management, including drug interactions, adverse effects, non-adherence, and polypharmacy. To optimize treatment outcomes, healthcare providers must adopt a comprehensive approach to medication management, involve interdisciplinary teams, and prioritize patient education. By addressing these drug-related problems systematically, healthcare professionals can improve the overall health and quality of life of these patients.

References:

  1. Gislason, G. H., Rasmussen, J. N., Abildstrøm, S. Z., Schramm, T. K., Hansen, M. L., Fosbøl, E. L., ... & Køber, L. (2011). Persistent use of evidence-based pharmacotherapy in heart failure is associated with improved outcomes. Circulation, 123(7), 692-703.
  2. Gnjidic, D., Hilmer, S. N., Blyth, F. M., Naganathan, V., Waite, L., Seibel, M. J., ... & Cumming, R. G. (2012). Polypharmacy cutoff and outcomes: five or more medicines were used to identify community-dwelling older men at risk of different adverse outcomes. Journal of Clinical Epidemiology, 65(9), 989-995.
  3. Meredith, S. (2016). The complexities of drug interactions. Healthcare, 4(3), 54.
  4. Page II, R. L., Linnebur, S. A., Bryant, L. L., & Ruscin, J. M. (2019). Inpatient management of comorbidities. In Chronic Care Management for Cardiac Disease (pp. 25-38). Springer.
  5. Sokol, M. C., McGuigan, K. A., Verbrugge, R. R., & Epstein, R. S. (2005). Impact of medication adherence on hospitalization risk and healthcare cost. Medical Care, 43(6), 521-530.
  6. Vrijens, B., De Geest, S., Hughes, D. A., Przemyslaw, K., Demonceau, J., Ruppar, T., ... & Dobbels, F. (2012). A new taxonomy for describing and defining adherence to medications. British Journal of Clinical Pharmacology, 73(5), 691-705.
  7. Yusuf, S., Teo, K. K., Pogue, J., Dyal, L., Copland, I., Schumacher, H., ... & Sleight, P. (2008). Telmisartan, ramipril, or both in patients at high risk for vascular events. New England Journal of Medicine, 358(15), 1547-1559.

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